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J. Yun Tso When J. Yun Tso left Hong Kong at age 17 to come to the United States, he recalls language and his college English courses as his most difficult challenges. By contrast, chemistry, physics, mathematics, and biology were relatively simple for the young scholar. Decades later, Tso likely remains one of the very few among us who might describe biochemistry and the intricacies of antibody humanization research as "simple.” Tso came to this country to pursue his vision of unlimited academic and professional opportunities and, since 1971, he's lived his dream. After earning his Ph.D. in Biochemistry from Purdue and completing post-doctoral fellowships at Purdue, Cornell University, and Stanford University, Tso accepted a position as staff scientist with Protein Design Labs of Fremont, California. Throughout his 16 years with this renowned biotech company, Tso has distinguished himself as a brilliant researcher. He advanced quickly from staff scientist to senior scientist and, in August 2001, was named Director of Oncology. Tso's current research efforts focus on the fight against cancer. He is a respected pioneer in antibody humanization—the process of humanizing key components of mouse antibodies and transforming them as "magic bullets" able to target human cancer cells. Today, five humanized antibodies are marketed for a range of serious diseases, and more than 25 new antibody-based products are expected to be approved within five years. Tso describes his efforts quite succinctly: You can work on a process in the lab for five or six years, and it might not look that great, he explains. But find the one thing that works, and it could change the world. For his outstanding contribution to the food, agriculture, and natural resources system, the Purdue College of Agriculture is proud to present the Distinguished Agricultural Alumnus Award to J. Yun Tso.
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